안녕하세요 예비 미국 간호사 선생님들
이번에는 Anti-coagulation drug 에 대해 공부해봅시다.
이 문제는 보통 passing level입니다.
What is anti-coagulant function?
>> They inhibit coagulation reaction, NOT dissolve clots
(Help to dessolve, NOT dissovle itself)
What dissolve clots ?
>> Tissue plasminogen activator (tPA)
Rule #1 Heparin vs Wafarin antidote
- Heparin: Protamine
- Wafarin: Vit K (Grean Leafy veggies)
Rule #2 aPTTvs INR
aPTT = Heparin
- Normal: 25-35 sec
- Therapeutic: 45-76 sec
* What happen aPTT is to high ?
>> Decrease Heparin rate
INR = Wafarin
- Normal: 2-3.5
- NO Grean Leafy veggies
Rule #3 Avoid 3G herbal during anticoagulant therapy
- Ginko
- Ginger
- Garlic
Rule #4 Avoid 3 foods during wafarin
- Broccoli
- Liver
- Spinach
Rule #5 NO NSAID during anticoagulant therapy
- Avoid "aspirin"
- Tylrentol is NOT NSAID
- NO Aclohol
** Estrogen = promote coalguation function
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